#16 - Prof David Nutt: The Neuroscience Of Psychedelics, Addiction, And How Drugs Help Us Understand The Brain


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By Mind Medicine Australia and Tommy Moore. Discovered by Player FM and our community — copyright is owned by the publisher, not Player FM, and audio is streamed directly from their servers. Hit the Subscribe button to track updates in Player FM, or paste the feed URL into other podcast apps.

Prof David Nutt is Neuropsychopharmacologist specialising in the research of drugs that affect the brain and conditions such as addiction, anxiety, and sleep. He is the chairman of Drug Science, a non-profit which he founded in 2010 to provide independent, evidence-based information on drugs. Nutt is the deputy head of the Centre for Psychedelic Research at Imperial College London. He and his team have published research into psilocybin for TRD, as well as neuroimaging studies investigating psilocybin, MDMA, LSD, and DMT.

In this episode we discuss:

  • How drugs help our understanding of the brain
  • Impact of prohibition on investigation and research
  • Key terms - decriminalisation, depenalisation, legalisation
  • Drug harm profiles - alcohol, lsd, mdma, psilocybin
  • Physiology and psychology of addiction
  • Brain-mind interplay
  • The psychedelic experience and its phenomena
  • The default mode network
  • Functional connectivity
  • Neuroplasticity
  • Why profound alterations in consciousness permit long-term changes
  • Serotonin's role in depression
  • Psilocybin vs SSRIs and the 5HT2a receptor
  • Psychedelics vs Psychedelic-assisted psychotherapies

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Learn more about David and his work:
Drug Science
The Drug Science Podcast
David Nutt on Twitter

Recent paper exploring Psilocybin vs SSRIs:
Serotonin and brain function: a tale of two receptors

20 episodes