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The goal is to have A Second Opinion be seen as the go to place for learning how to improve health and health care. Together we will have conversations with the health thought leaders, the entrepreneurs, the clinicians, the policy makers, the business leaders, and the consumers— to better understand how we all can improve health and well-being — of ourselves as individuals, of our families — and of our communities. We achieve this through education and engagement at the nexus of policy, medi ...
 
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As the nation and world continue to grapple with COVID-19, there is much to learn about how to improve our health preparedness in the midst of crisis. Nashville is one of the first communities in the nation to do a comprehensive review of lessons learned from Nashville's health, business and community response to the pandemic. Today, we’re going to…
 
Allan Sniderman is a highly acclaimed Professor of Cardiology and Medicine at McGill University and a foremost expert in cardiovascular disease (CVD). In this episode, Allan explains the many risk factors used to predict atherosclerosis, including triglycerides, cholesterol, and lipoproteins, and he makes the case for apoB as a superior metric that…
 
Today’s episode of The Drive is a rebroadcast of the conversation with Rick Johnson (originally released January 6th, 2020). This episode was one of the most popular discussions to-date and is a prelude to an upcoming follow-up discussion which will be coming out in February 2022 along with the release of Rick’s new book. In this episode, Rick John…
 
This episode is brought to you by the Blue Cross Blue Shield Association. Blue Cross and Blue Shield companies are in every ZIP code in every state, working to improve health and expand access to care. Community by community. For the health of America. I’m joined today by the top leadership of Seniorlink, an innovative company that provides coachin…
 
Today we’re sharing with you a special bonus episode. As we head into our second holiday season in the midst of a global pandemic, I sit down with NIAID Direction & President Biden’s Chief Medical Advisor Dr. Anthony Fauci for the Bipartisan Policy Center’s discussion on COVID-19, the Forecast for the Holidays, 2022 & Beyond. We touch on when we’ll…
 
Tom Spann is CEO of Brightside, a comprehensive financial health engagement platform that partners with employers to give employees and their families the financial care they need. Previously, he was the founding CEO of Accolade, which today helps over 2 million people navigate the health system. Our discussion today is centered on how one’s person…
 
In this “Ask Me Anything” (AMA) episode, Peter and Bob discuss all things related to GLP-1 agonists—a class of drugs that are gaining popularity for the treatment of obesity. They cover the discovery of these peptides, their physiology, and what it is they do in their natural state. Next, Peter and Bob break down a recently published study which sh…
 
James Clear is the author of the New York Times bestseller Atomic Habits. His extensive research into human behavior has helped him identify key components of habit formation and develop the “Four Laws of Behavioral Change.” In this episode, James provides insights into how both good and bad habits are formed, including the influence of genetics, e…
 
We are joined again today by one of our very first guests on the show. Sam Quinones is an award-winning journalist and the New York Times bestselling author of Dreamland: The True Tale of America’s Opiate Epidemic. Two years ago, Sam and I discussed how opioid addiction had transformed the health and healthcare landscape of our nation. Today, Sam i…
 
David Nutt is a psychiatrist and a neuroscientist at Downing College, Cambridge. His research focuses on illicit drugs—their harm, classification, and potential for therapeutic use in psychiatry. In this episode, David discusses his framework for assessing the potential harm caused by common recreational drugs and explains how they are regulated, w…
 
Dr. Kevin Churchwell is the president and CEO of Boston Children’s Hospital, ranked the number one pediatric hospital in the nation. There, they treat more rare and complex pediatric cases than any other hospital in the world. On today’s show, Dr. Churchwell shares his inspiring story of how he went from being a practicing physician to leading majo…
 
Robert (Bob) Gatenby is a radiologist who specializes in exploring theoretical and experimental models of evolutionary dynamics in cancer and cancer drug resistance. He has developed an adaptive therapy approach for treating cancer which has shown promise in improving survival times with less cumulative drug use. In this episode, Bob explains what …
 
Dr. Emily Wang is a professor in the Yale School of Medicine and directs Yale’s new SEICHE Center for Health and Justice, which works to stimulate community transformation by identifying the legal, policy, and practice levers that can improve the health of individuals and communities impacted by mass incarceration. Today with Dr. Wang, we’re coveri…
 
In this “Ask Me Anything” (AMA) episode, Peter and Bob discuss all things related to testosterone: what happens when testosterone levels are low, and the potential benefits and risks of testosterone replacement therapy (TRT). They explain the physiology of testosterone, how it works, and how its level changes over the course of a person's life. The…
 
On October 6th, the United Way of Greater Nashville hosted a timely and compelling discussion on “Healthcare Disparities in Our Own Backyard.” The panel was made possible by the United Way’s de Tocqueville Society, a now-global society that was founded in 1981 by my brother Dr. Tommy Frist, Jr., to deepen relationships between the United Way and co…
 
Jeremy Loenneke has a Ph.D. in exercise physiology, a Master’s in nutrition and exercise, and is currently the director of the Kevser Ermin Applied Physiology Laboratory at the University of Mississippi, where he focuses his research on skeletal muscle adaptations to exercise in combination with blood flow restriction (BFR). In this episode, Jeremy…
 
Dr. Harvey Fineberg is president of the Gordon and Betty Moore Foundation. He previously served as president of the U.S. Institute of Medicine (now the National Academy of Medicine), as provost of Harvard University, and as dean of the Harvard Chan School of Public Health. Our wide-ranging discussion today hits on so many topics, including the role…
 
Lance Armstrong is a legendary figure in professional cycling having won seven consecutive Tour de France titles but also a controversial figure facing scrutiny for the use of performance enhancing drugs. In this episode, Lance takes us through his meteoric rise to one of the most famous athletes in the world and his equally accelerated fall from g…
 
Steve Rosenberg is the Chief of Surgery at the National Cancer Institute, a position he has held continuously for the past 47 years. Steve is a pioneer in the field of immunotherapies for cancer and a recipient of nearly every major award in science. In this episode, Steve discusses his inspiration for devoting his career to cancer research and des…
 
This episode is brought to you by MEDHOST, a Trusted EHR for Healthcare Facilities. To learn more, go to Medhost.com. Dr. Scott Gottlieb is the 23rd commissioner of the Food and Drug Administration, serving from 2017 through 2019. Today, he’s a fellow at the American Enterprise Institute, serves on the board of Pfizer, and is one of the most knowle…
 
In this “Ask Me Anything” (AMA) episode, Peter and Bob discuss the longevity benefits from greater cardiorespiratory fitness (CRF) and greater muscle mass and strength. Conversely, they dive deep into the literature showing a rapid increase in morbidity and mortality risk as fitness levels decline with age. They also try to tease out the relative c…
 
This episode is brought to you by MEDHOST, a Trusted EHR for Healthcare Facilities. To learn more, go to Medhost.com. Dr. Keith Churchwell is the president of Yale New Haven Hospital. A strategic and innovative leader, Dr. Churchwell is leading Yale New Haven into the new era of hospital care with an eye towards equity and diversity. With his roots…
 
Matt Kaeberlein is globally recognized for his research on the biology of aging and is a previous guest on The Drive. In this episode, Matt defines aging, the relationship between aging, chronic inflammation, and the immune system, and talks extensively about the most exciting molecules for extending lifespan. He discusses the current state of the …
 
Dr. Kelly Arnold is a pioneering physician who founded Clinica Medicos, a medical clinic designed to meet the unique needs of Chattanooga, Tennessee’s Latino community. Will an entirely bilingual medical staff and a commitment to address all patients needs in a culturally sensitive approach, the clinic is based on a principle that no one who walks …
 
Lawrence Wright is the author of The Looming Tower: Al-Qaeda and the Road to 9/11 which won the 2007 Pulitzer Prize for general nonfiction and was named one of Time's top 100 books of all time. In this episode, released just before the 20th anniversary of the September 11th attacks, Lawrence and Peter discuss the book and the lasting impact of that…
 
Today we are doing a deep dive into the revolutionary new field of synthetic biology. I’m thrilled to be joined by Dr. Jason Kelly, the CEO and co-founder of the company that’s leading this revolution, Ginkgo Bioworks. Ginkgo is the largest designer of synthetic DNA in the world, and programs cells for customers in the chemical, pharmaceutical, foo…
 
This episode is brought to you by the Blue Cross Blue Shield Association. Blue Cross and Blue Shield companies are in every ZIP code in every state, working to improve health and expand access to care. Community by community. For the health of America. Today we’re focusing in on rural behavioral health, looking at Montana as an example for some of …
 
Today we’re having a compelling discussion about pricing in healthcare. I’m joined by three thought leaders who are disrupting the status quo in both the business and policy arenas. By popular demand, we’ve invited back my longtime friend and colleague, Professor Larry Van Horn. Larry is a renowned expert and researcher on health care management an…
 
In this “Ask Me Anything” (AMA) episode, Peter and Bob answer numerous follow-up questions to recently discussed deep-dive topics such as the use of continuous glucose monitors and getting the most from zone 2 exercise. They also discuss the incredible feats of cyclists in the Tour de France through the lens of the amazing performance physiology re…
 
Esther Perel is a psychotherapist and New York Times bestselling author who is an expert on modern relationships. In this episode, Esther describes how being a child of parents who narrowly survived the Holocaust shaped and influenced her perspectives and ultimately led to her to a career in therapy. She discusses how the generational differences i…
 
Mike Uchrin is the CEO & Co-Founder of Monogram Health, an innovative, exciting new company that’s transforming one of the most complex and underserved areas of healthcare: managing chronic kidney disease and end-stage renal disease. Based in Nashville, Tennessee, Monogram partners with health plans to fill a systemic gap in kidney disease care wit…
 
Steve Austad is a distinguished professor of biology at the University of Alabama and director of one of the Nathan Shock Centers of Excellence in aging biology. Steve's current research seeks to understand the underlying causes of aging, specifically with a long-term goal of developing medical interventions that slow the age-related decay of human…
 
Dr. Rochelle Walensky is the 19th Director of the Centers for Disease Control and Prevention. Prior to leading the CDC, she served as Chief of the Division of Infectious Diseases at Massachusetts General Hospital and Professor of Medicine at Harvard Medical School. Dr. Walensky was on the frontlines of the COVID-19 pandemic and conducted research o…
 
Dr. Shantanu Nundy is a primary care physician, technologist, and business leader who serves as Chief Medical Officer for Accolade, which helps over 2 million people navigate the health system. In addition, he practices primary care in the greater Washington, DC, area and serves as a senior advisor to the World Bank and a lecturer in health policy …
 
In this “Ask Me Anything” (AMA) episode, Peter and Bob dive deep into cancer screening, including why it’s important, what you need to know about a test, and Peter’s approach with patients. They specifically discuss various screening methods, explain important terms like sensitivity and specificity, and how layering and stacking different tests in …
 
This past year has sparked a major care transition and greater awareness of the need for and value of home-based care. And that is our topic today – focusing on Landmark Health I have with me today two experts in the field: Adam Boehler, the founder and CEO of Landmark Health for its initial five years, and since then, former head of the Center for…
 
This episode is brought to you by the Blue Cross Blue Shield Association. Blue Cross and Blue Shield companies are in every ZIP code… in every state, working to improve health and expand access to care. Community by community. For the health of America. Jacob Sattelmair is Co-Founder and CEO of Wellframe, a digital health management company… provid…
 
Katherine Eban is an award-winning investigative journalist who previously appeared on The Drive to discuss the widespread fraud in the generic drug industry. In this episode, she discusses the content of her recent Vanity Fair article, which examined the evidence for the theory that the COVID-19 pandemic resulted from a virus lab escape as opposed…
 
Hugh Jackman is an award-winning actor and an overall fascinating and introspective individual. In this episode, Hugh reflects upon his acting career, including how he navigated many tough decisions that led to important professional turning points for him. Peter and Hugh have an intimate discussion related to handling professional criticism, self-…
 
Dr. William Schaffner, a familiar and nationally recognized face and trusted voice on all matters COVID during the pandemic, is an infectious disease colleague of mine … when I was doing heart and lung transplants at Vanderbilt University medical enter. Today he is the medical director and past president of the National Foundation for Infectious Di…
 
On June 30th, community health collaborative NashvilleHealth, the Metro Nashville Public Health Department and the Nashville Health Care Council hosted a timely discussion on Covid and re-opening Music City, USA – Nashville, Tennessee. We’re sharing this discussion with you as a close look at how one southern city is handling vaccine distribution, …
 
Today we’re sharing with you a special episode. I recently sat down with Andy Slavitt for Book TV’s After Words program, where we discussed in detail Andy’s new book: Preventable: The Inside Story of How Leadership Failures, Politics, and Selfishness Doomed the U.S. Coronavirus Response. Andy Slavitt is uniquely qualified to tell this story. As the…
 
Gary Taubes is an investigative science and health journalist and a best-selling author. In this podcast, Gary explains how he developed a healthy skepticism for science as he was transitioning from being a physics major to beginning as a science journalist. He talks about how he was particularly drawn to sussing out “pathologic science,” telling t…
 
Today we’re sharing with you a discussion we had on June 22nd with the Cato Institute on medical malpractice litigation, legislation, and the future of reform. I’m joined by Professor David Hyman, a physician, the Scott K. Ginsburg Professor of Health Law & Policy at Georgetown University Law Center, and an adjunct scholar at the Cato Institute. He…
 
Dr. Patricia Corby is Associate Professor of Oral Medicine and Associate Dean of Translational Research at Penn Dental Medicine. Her work focuses on the importance of providing dental services alongside critical public healthcare services, like cancer treatment. In this episode, Pat provides an overview of dental anatomy, the importance of oral hyg…
 
Adam Schechter is the Chairman, President, and CEO of Labcorp, a leading global life sciences company, with a presence in over 100 countries and annual revenue of $14 billion. LabCorp has become a household name during the global pandemic, and Adam was only a few months into his role as CEO when Covid-19 hit. He has a fascinating story of pivoting …
 
In this “Ask Me Anything” (AMA) episode, Peter and Bob dive deep into blood glucose and why it matters so much with respect to metabolic health and longevity. They explain the need to pay close attention to metrics like average blood glucose, glucose variability, and peak glucose numbers. Additionally, Peter explains why he encourages all his patie…
 
Dr. Marty Makary is a New York Times bestselling author, Johns Hopkins gastrointestinal surgeon and Professor of Health Policy. His newest book, The Price We Pay, is just out now in paperback with new Covid-19 updates, and has been called the “The Big Short” of American Medicine. Marty’s research has led to actionable solutions that reduce waste an…
 
Amanda Grant Smith is a geriatric psychiatrist with decades of experience treating patients with dementia and Alzheimer's disease. In this episode, Amanda shares how she developed a passion for geriatric psychiatry as a means to support dementia patients. She explains how to recognize, define, and diagnose dementia—a process that still remains some…
 
Today’s episode is one of the most fun, insightful, thought-provoking discussions I’ve had on the show. Our guest is the only physician executive I know who started as a disc jockey, and went on to become one of the most transformational thought leaders in the healthcare space today. Dr. Stephen Klasko is the President & CEO of Thomas Jefferson Uni…
 
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