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Divya A. Khandekar, PharmD, MS (Twitter: @pharmdiv) describes the etiology of febrile neutropenia in patients with hematological malignancies, summarizes guideline-based recommendations for antibiotic discontinuation in patients with febrile neutropenia and discusses primary literature supporting early antibiotic discontinuation in patients with fe…
 
On this episode, we review the pharmacology/pharmacotherapy of anticoagulants. We compare and contrast the various agents currently available, and briefly discuss their roles in various disease states (VTE, Afib, etc). Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episo…
 
Andrew J. Jatis, PharmD (Twitter: @jatis_rx) reviews the pharmacology and drug characteristics of dalbavancin and oritavancin, describes current literature assessing the safety and efficacy of FDA approved and off-label indications for lipoglycopeptide use in clinical practice and discusses pharmacoeconomic implications of lipoglycopeptide use in c…
 
On this episode, AJ and I discuss the OTC cognitive support supplement called Prevagen. We review the data that supposedly justifies this product being the top seller in this supplement space. These are just our opinions based on the available data. If you disagree, we would love to hear why. Thanks for listening! We want to give a big thanks to ou…
 
On this episode, we cover various menstruation-related disorders. We review amenorrhea, heavy menstrual bleeding, PCOS, dysmenorrhea, PMS, and PMDD. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners …
 
Kaylee A. Clark, PharmD describes the basic principles of maintenance therapies after allogeneic HSCT, discusses evidence and guideline recommendations for maintenance therapies after allogeneic HSCT for acute lymphoblastic leukemia and reviews evidence and guideline recommendations for maintenance therapies after allogeneic HSCT for acute myeloid …
 
Kyle J. Eickman, PharmD, describe the goals of six sigma methodology and review examples of its application within pharmacy dispensing, reviews DMAIC methodology and describes how lean and six sigma can be used to achieve the same goals of patient safety. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the…
 
Dimple R. Dhakal, PharmD describes the pharmacodynamics and pharmacokinetics of methadone, identifies and discusses clinical practice guidelines for the safe use of methadone and evaluates evidence for CYP2B6-guided methadone use. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm…
 
On this episode, we review various adult immunizations and discuss the changes that were included in the 2022 ACIP updates. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to c…
 
On this episode, we give an overview of cystic fibrosis. We start with some back ground information including some tests involved with the diagnosis. We then discuss the various treatments used to manage the disease and improve quality of life. Thanks for listening! We want to give a big thanks to our main sponsor Pyrls. Try out their drug informat…
 
Julie L. Cunningham, PharmD, BCPP; M. Zeeshan Rizwan, PharmD, BCPS, BCCCP; Christi A. Jen, PharmD, BCPS, FASHP, FAzPA; and Kristina L. Wescott, PharmD, BCPS identify appropriate non-stigmatizing language related to opioids and addiction in the context of patient care discussions, discuss risks for opioid harms related to individual risks at points …
 
Hannah M. Brokmeier, PharmD, describes the pathophysiology behind the pharmacologic targets in ACLS, discusses the role of vasopressin, steroids, and epinephrine in cardiac arrest management, and explains the mechanism and evidence behind administering adjunct agents during ACLS. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Prog…
 
On this episode, we discuss the 2022 GOLD guidelines for COPD. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episode…
 
On this episode, we discuss pulmonary arterial hypertension (PAH) and the pharmacotherapy options that are currently available. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We have continued to partner with freeCE.com to provide listeners with the opportunity …
 
On this episode, we are joined by Jessa Mae Sabate and Nichole Arroyo (4th year MUSC PharmD candidates) to discuss a patient case looking into the management of advanced liver disease. We discuss hepatic encephalopathy and treatment options for hepatitis C. We also review the management of cholestatic pruritus, insomnia, and some other behavioral h…
 
Lauren M. Dolly, PharmD, recalls the etiology and pathophysiology of TRD, discusses the role of pharmacogenomics in L-methylfolate for TRD, selects a preferred agent for a patient with TRD with evidence to support its use. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.…
 
Pooja Ojha, PharmD, describes what bias in artificial intelligence entails, discusses implications of bias in artificial intelligence, evaluates mitigation strategies for bias in artificial intelligence. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schram…
 
Molly A. McCord, PharmD, describes pediatric-specific differences in pharmacokinetics as it applies to commonly used immunosuppressants, discusses concerns related to medication formulations, monitoring, and adherence in the pediatric population, reviews pediatric solid organ transplantation pharmacotherapeutic controversies in immunosuppression an…
 
On this episode, we review the management of multiple sclerosis. We start with discussing some background information about the disease. We then review the various pharmacotherapy options that are available and even some head-to-head comparative data. We close with an overview of the medications used for the management of symptoms associated with M…
 
Mackenzie L. Bevry, PharmD, identifies the key populations that currently have evidence for improved outcomes with pre-emptive pharmacogenomic testing, describes the difference between clinical and direct-to-consumer pharmacogenomic testing, recognizes some of the currently available pharmacogenomic testing options available to patients. For more p…
 
Michaela E. Wermers, PharmD, defines therapeutic options and appropriate dosing methods for oral iron replacement, identifies the various intravenous iron therapies and discuss product differences, reviews literature of select disease states in which intravenous iron therapy is utilized. For more pharmacy content, follow Mayo Clinic Pharmacy Reside…
 
On this episode, we discuss the ACR guidelines for managing rheumatoid arthritis. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We continue to partner with freeCE.com to provide listeners with the opportunity to claim 1-hour of continuing education credit for s…
 
On this episode, we discuss the treatment options available for managing an H. pylori infection. We discuss how resistance rates have changed the recommended first-line options, and we cover the new combo paks that utilize vonoprazan (a potassium-competitive acid blocker) for acid suppression. Thanks for listening! We want to give a big thanks to o…
 
Stacy A. Bernard, PharmD, BCPS, BCTXP, reviews anti-hypertensive agents and their use in the longitudinal care of a solid organ transplant patient, relates drug-drug interactions between statins and immunosuppressive therapies to dyslipidemia treatment decisions in a solid organ transplant patient, discusses short- and long-term considerations when…
 
Marissa Z. Powell, PharmD, describes mechanisms of chronic graft versus host disease, recognizes historical approaches to treatment of chronic graft versus host disease, discusses recent updates in chronic graft versus host disease therapy. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett …
 
On this episode, we review the 2022 AHA/ACC/HFSA guidelines. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We continue to partner with freeCE to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. To earn c…
 
Hosted by Garrett E. Schramm, Pharm.D., Mayo Clinic Pharmacy Grand Rounds is a weekly podcast for pharmacists, physicians, physician assistants, and nurse practitioners who are interested in learning more about clinical pharmacology topics. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett …
 
Danielle M. Hess, PharmD, BCPS, describes the mechanism of action of ketamine as it relates to chronic pain relief, evaluates literature depicting the role of ketamine for chronic pain management, and defines patient scenarios and/or conditions in which guidelines recommend the potential use and safety precautions of ketamine for chronic pain. For …
 
On this episde we review various food allergies and food intolerances (specifically celiac disease). Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We continue to partner with freeCE to provide listeners with the opportunity to claim 1-hour of continuing educati…
 
On this episode, we are joined by Austin Dew, Emilie Parkman, and Kaleigh Steelman, all of which are P4 students. We are discussing a patient case dealing with a patient suffering from intermittent explosive disorder. We also discuss the patients diabetes, CVD, and more. Thanks for listening! We want to give a big thanks to our main sponsor Pyrls. …
 
Cassandra J. Schmitt, PharmD, determines risk factors associated with severe COVID-19 disease progression, discusses efficacy and safety outcomes of novel agents for the outpatient treatment of COVID-19, identifies the ideal candidate to receive treatment with oral molnupiravir, nirmatrelvir/ritonavir, or intravenous monoclonal antibodies for mild-…
 
On this episode, we are joined by P4 MUSC students Kaleigh Steelman and Emilie Parkman. We disucss the management and treatment options for atopic dermatitis. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We continue to partner with freeCE to provide listeners …
 
Jia Yin Townley, PharmD, BCPS, describes the pathophysiology of short bowel syndrome, identifies the medications used to manage short bowel syndrome and recognizes ways to optimize medication regimens for short bowel syndrome patients. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Sc…
 
On this episode, we discuss the various treatment options available for managing allergic rhinitis. Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We continue to partner with freeCE to provide listeners with the opportunity to claim 1-hour of continuing educatio…
 
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